By car: There is one main road entrance to the hospital site via the island where the A4101 Pensnett Road splits to become the A4101 Kingswinford Road.

By bus: The terminus is located outside the main entrance and there are also stops nearby in Pensnett Road and Kingswinford Road. Buses to Dudley, Kingswinford and Stourbridge run frequently throughout the day.

By rail: The nearest railway stations to Russells Hall Hospital are Cradley Heath, Dudley Port and Tipton.